Vitamin C plays a role in enzyme function in your cells, and low vitamin C levels can make it harder to oxidize fat during exercise, according to a Nutrition and Metabolism study published in 2006. While the jury is still out on whether grapefruit can directly reduce body fat, it does offer beneficial vitamin C - a nutrient you'll want in your diet for fat loss. Larger, long-term studies are still needed to know if grapefruit truly aids in fat loss. These conflicting results mean that grapefruit might not have a significant effect on weight loss for everyone or that it might not offer added health benefits if you're already eating a healthy diet. However, a more recent human study, published in Metabolism in 2012, found that healthy people who ate grapefruit as part of a nutritious diet didn't lose any more weight than people who just ate healthfully, without a particular focus on grapefruit. And a human study, published in the Journal of Medicinal Food in 2006, found that people with obesity who drank grapefruit juice, ate grapefruit or took a grapefruit extract supplement lost more weight over the 12-week study period than those who didn't get grapefruit. Mice fed grapefruit juice gained less weight than mice that didn't get grapefruit juice - even though both groups followed a diet designed to trigger weight gain, reports a study published in PLoS One in 2014. There is some preliminary - and conflicting - evidence about grapefruit juice and belly fat.
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